What is the primary active component of neonicotinoids?

Neonicotinoids are a class of insecticides that primarily function by targeting the central nervous system of insects. They are chemically similar to nicotine and exert their effects by binding to nicotinic acetylcholine receptors in the neurological pathways of pests. This binding interferes with synaptic transmission, leading to paralysis and ultimately the death of the insect.

The design of neonicotinoids allows them to be effective at low doses, making them potent against a variety of pest species. Their specificity for insect receptors over mammalian receptors contributes to their effectiveness while offering a level of safety for non-target organisms. Therefore, understanding the action mechanism of neonicotinoids reveals why they are prominent in agricultural pest management.